We surmise that results obtained from the experiments described in this section cannot serve to understand the role of INaL in arrhythmogenesis.
1. Van Driessche W, Lindemann B: Amount dependency out of currents compliment of single salt-choosy skin pores in frog facial skin. Nature. 1979; 282 (5738): 519-520 PubMed Abstract | Blogger Complete Text
This means this new good results put forward from this manuscript was not rationalized and i dont approve the fresh new manuscript inside means
The fresh authors features made clear a number of the questions We elevated inside the my earlier in the day feedback. Unfortunately, the significant trouble haven’t been treated from this posting. Once i stated in my personal past remark, We deem it unlikely that every people circumstances might be repaired simply of the several added sentences. Alternatively you can still find particular simple questions on the fresh design and, very critically, into investigation.
It indicates new solid conclusions put forward through this manuscript was not rationalized and that i dont agree the latest manuscript in this setting
The fresh new article writers keeps clarified several of the questions I elevated in my past remark. Sadly, all the big dilemmas haven’t been treated from this posting. Whenever i stated in my personal prior remark, I consider they unrealistic that every men and women products will likely be fixed merely by the a number of additional sentences. Instead there are particular simple concerns on experimental structure and you can, really significantly, towards the study.
- The best issue is whenever We then followed the fresh dysfunction away from the methods in the earlier version it actually was you’ll be able to so you can decode, which have almost best precision, any random stimuli brands I picked. Come across to possess types of this reanalysis. No matter whether i pretend the genuine stimulus searched on a later go out or is consistently switching between signal and you can quiet, the brand new decryption is always alongside primary. This will be a sign that decoding doesn’t have anything to do into actual stimulus read by Sender but is opportunistically exploiting other keeps about studies. The latest manage study the brand new people performed, reversing the fresh new stimulus brands, do not target this problem whilst is suffering from equivalent disease. Fundamentally, exactly what the classifier is allegedly using it’s time who’s got enacted since tape been.
- The main cause of this really is allegedly the experts utilized non-separate research to possess knowledge and you may assessment. Of course I’m sure precisely (get a hold of point step 3), haphazard testing one half of data products away from an EEG shade commonly independent data. Recurring the analysis five times – the brand new handle studies the brand new experts did – is not an adequate cure for target it question. Randomly shopping for products out-of an occasion show which has slow alter (like the slow trend craft you to presumably reigns over these tracks less than these circumstances) have a tendency to invariably incorporate strong temporal correlations. Discover TemporalCorrelations.jpg in for 2D occurrence histograms and you will a correlation matrix proving which.
- As the modified tips section provides increased detail today, it still is unclear about just what data were utilized. Conventional category analysis statement what research provides (usual columns regarding the analysis matrix) and you may just what findings (usual rows) were utilized. Some thing would-be a feature however, usually this is exactly the fresh new various other EEG avenues otherwise fMRI voxels etcetera. Findings are usually go out circumstances. Here I suppose the authors turned the fresh new raw samples on the an effective additional place playing with principal role investigation. This is not stated in case your dimensionality try faster utilising the eigenvalues. Regardless, I suppose the information products (built-up during the 128 Hz) was up coming utilized due to the fact findings therefore the EEG streams turned of the PCA were used while the features. The stimulus labels was tasked given that Into the otherwise From per test. A couple of 50% out-of samples (and you will labels) was then picked at random to possess education, therefore the rest was utilized having assessment. So is this proper?